Evorel® Conti
What is Evorel® Conti and what it is used for?
The name of your medicine is Evorel Conti 50/170 micrograms per 24 hours Transdermal patch. It is called Evorel Conti in this leaflet. It belongs to a group of medicines called hormone replacement therapy (HRT).
Evorel Conti contains two medicines:
- An oestrogen (estradiol)
- A progestogen (norethisterone)
They are both female hormones.
Evorel Conti comes in a pack that helps you to remember when to change your patches (see section 3 ‘How to use Evorel Conti’). Each pack contains eight patches.
The hormones are spread evenly in each patch. They pass slowly into your body through the skin
What is Evorel® Conti used for?
Evorel Conti is used:
• For the symptoms of the menopause
It is suitable for women who have been post-menopausal for 6months. This is usually taken to be 18 months after the last period (menstrual bleed), but your doctor will advise you.
How Evorel® Conti works
Evorel Conti is known as ‘continuous combined’ HRT. This is because both hormones in the patch are released all the time.
Evorel Conti patches replace the oestrogen that is normally released by the ovaries. However, in women who still have a womb, taking an oestrogen hormone regularly may cause the lining of your womb to build up and get thicker
• This means it is necessary to add a progestogen hormone to the oestrogen
• This helps shed the lining of the womb and stop any problems happening This is why Evorel Conti patches also contain a progestogen.
Most women do not have a regular monthly period with Evorel Conti. However, bleeding or spotting does often occur in the first few months until treatment settles down.
Evorel Conti is not a contraceptive. If it is less than 12 months since your last menstrual period or you are under 50 years old, you may still need to use additional contraception to prevent pregnancy. Speak to your doctor for advice.
How to Use Evorel® Conti
Always use Evorel Conti exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure. Your doctor will aim to reduce your symptoms with the lowest possible dose for the shortest amount of time.
When to start using Evorel® Conti
Put an Evorel Conti patch on at the end of a treatment cycle or two weeks after you finish using another HRT product if:
- You are changing from an HRT medicine that gives you a withdrawal bleed
If you are using another type of HRT:
- The day you start will depend on the type of HRT you have been using
Talk to your doctor if you are not sure which type of HRT you are using.
You may put an Evorel Conti patch on at any time if:
- You have not been using another type of HRT
Using the patches
The patches need to be changed twice a week. Start a new pack of Evorel Conti as soon as you finish one. Do not leave a break between packs.
Changing your patches
- You must change the patches twice a week to give your body a steady supply of hormones.
There is enough hormone in each patch to last for several days - Change your patch on the same two days every week. This will mean that one patch is on for three days and the next patch for four days
- For example, if you apply your first patch on a Monday, change it on Thursday and again on the following Monday
Where to apply the patch
Stick the patch onto a hairless area of skin below the waist. Most women prefer to wear the patch on the thigh or bottom.
- Do not apply on or near the breasts
- Do not put it on top of cuts, spots or anywhere the skin is irritated
- Do not use cream, moisturiser or talc before applying the patch
- Do not apply the patch on the same area of skin twice in a row
- It can be worn under loose areas of clothing. Do not wear a patch under elasticated areas or a tight waistband
- Apply the patch to clean, dry, cool skin as soon as you open the protective pouch
What happens if a patch falls off?
Apply a new patch but keep to your original ‘patch change’ days. If you have just had a bath or a shower, wait until your skin cools before applying the new patch. Talk to your doctor if you need more patches.
What happens if you forget to change the patch?
Change it as soon as you remember and then keep to your original ‘patch change’ days. You may get some bleeding and spotting like a period during this time.
Frequently asked questions about Evorel®
What happens if I use more Evorel® Conti than I should?
It is unlikely that you will have too much of the hormones in Evorel Conti. The most common symptoms of having too much oestrogen or progestogen in your body are:
- Tender breasts
- Feeling sick (nausea) or being sick
- Unexpected vaginal bleeding
- Stomach pain or bloating
- Feeling depressed
- Tiredness
- Acne
- Growth of body or facial hair
Removing the patch can reverse the effects of too much oestrogen and/or progestogen. Talk to your doctor or pharmacist before using any more patches.
Can I use Evorel® Conti as a contraceptive?
The levels of hormone from the patches are too low to act as a contraceptive. Talk to your doctor for advice on contraception.
What about Everyday activities with Evorel® Conti?
- You can have a bath or shower as normal. Do not scrub too hard as this can loosen the edges of the patch
- You can go swimming. The patch will not be affected
- You can exercise and play sports. However, do not wear the patch under tight clothing or waist bands
- You can sunbathe. However, keep the patch covered, out of direct sunlight
What possible side effects may I experience with Evorel® Conti?
Like all medicines, this medicine can cause side effects, although not everybody gets them.
The following diseases are reported more often in women using HRT compared to women not using HRT:
- breast cancer
- abnormal growth or cancer of the lining of the womb (endometrial hyperplasia or cancer)
- ovarian cancer
- blood clots in the veins of the legs or lungs (venous thromboembolism)
- heart disease
- stroke
- probable memory loss if HRT is started over the age of 65
